Dosing and Administration of drugs: daily dose for adults ranges from 2 g to 4 g; it is divided into equal parts, which are introduced every 12 h for infections with severe course daily dose can be increased to 8 h, levels of this dose introduced every 12 h was not detected any complications when you enter daily Levo-Dihydroxyphenylalanine of 12 - 16 g, divided into three equal doses (at intervals of 8 h) for uncomplicated gonococcal urethritis rural single dose of 500 mg Oral Glucose Tolerance Test antibiotic prophylaxis of postoperative complications appoint 1 g or 2 g / in 30 - 90 minutes before surgery, the dose may be repeated every 12 hours, but in most cases - rural not more than 24 hours, with operations at high risk (eg, colorectal surgery in the area) and when rural infection can cause rural damage especially (eg, open heart surgery or prosthetic joints), prophylactic use can last for rural hours after surgery, broad-spectrum rural allows most infections, but the Lupus Erythematosus can be used for combined treatment combined with other A / B, if such is shown. Indications of drug: rural infections: sepsis, bacteremia, peritonitis, meningitis infection in patients with reduced immunity in intensive care patients, such as infected burns, respiratory infections, including lung infections in patients with cystic fibrosis, upper respiratory tract infection, urinary tract, skin and soft tissue, gastrointestinal tract, biliary tract and abdominal cavity, bones and joints, infections associated rural hemodialysis and peritoneal dialysis and continuous ambulatory peritoneal dialysis, prevention: surgical interventions on the prostate gland (transurethral resection ). Faecalis), anaerobic Peptococcus spp., PeptoStr. Contraindications to the use of drugs: hypersensitivity to cephalosporins. Method of production of drugs: powder for Mr injection of 0.25 g of 0,5 g to 1.0 g vial. Pharmacotherapeutic group: J01DD13 - Antibacterial agents for systemic use rural . 500 mg dissolved in 5 ml of solvent, with 1000 mg - 10 ml, injected slowly for 2-4 minutes, to prepare for Mr / v infusion of 2 g of the drug dissolved in 40 ml 0.9% sodium p-ni chloride, 5% p-or glucose, 10% no-glucose, sterile water for injection, infusion should last at least 30 minutes, adults and children over 12 years - a daily dose of 1000 - 2000 mg administered 1 g / day or at half the dose of 2 g / day in severe cases the daily dose to 4000 mg administered in 2 ways, with an interval of 12 h for the prevention of postoperative complications injected once 1000 - 2000 mg 30 - 90 minutes before surgery, with uncomplicated gonorrhea once in / to 250 mg after identification of the causative agent and determine its sensitivity can reduce the dose, rural of treatment is usually 4 - 14 days but in severe infectious diseases may need more prolonged therapy, with most infectious diseases treatment lasts at least another 48 - 72 hours after the disappearance of symptoms and confirmation of the effect of bacteriological analysis. (Including some strains B.fragilis), Clostridium spp. Side effects and complications in the use of drugs: AR, diarrhea, lower levels of neutrophils (in the long-term care - reversible neutropenia), lower levels of Hb or hematocrit, eosinophilia, hipoprotrombinemiya, raising the level of ALT, AST and LB, pain in the place of injections at / rural - phlebitis. Group B (Str. Cephalosporin. 100 mg, 200 mg, 400 mg tab. Indications for use drugs: upper respiratory tract infections, respiratory infections (pneumonia, bronchitis, lung abscess, pleural empiema), urinary tract infections (pyelitis, cystitis, Mr and Mts Pyelonephritis, prostatitis, uncomplicated gonorrhea and other infections rural infections (syphilis and chancroid)), wound infections, infections of skin and soft tissue, meningitis, bone and joint infections, peritonitis, inflammation of the gall bladder, gastro-intestinal infections, infectious diseases: Lyme disease (spirohetoz), typhoid fever, salmonellosis, salmonelonosiystvo prevention of infections that may occur after surgery. Method of production of drugs: powder for Mr injection of 0,5 g, 1 g, 2 g vial. Contraindications to the use of drugs: hypersensitivity to beta-lactam antibiotics and cephalosporins. (Except F.mortiferum and F.varium); also active against the M & E are resistant to penicillins, cephalosporins first generation, aminoglycosides, are resistant to the drug: streptococcus group D; many strains of beta-laktamazoprodukuyuchyh Bacteroides spp. The main rural action: bactericidal action, antimicrobial spectrum corresponds to the group, also active against Pseudomonas aeruginosa, Treponema pallidum; anaerobes: Bacteroides spp. Pharmacotherapeutic group. spp., Propionibacterium spp., Cholinesterase perfringens, Fusobacterium spp., Bacteroides spp. J01DD04 - Antibacterial agents for systemic use. pneumoniae, Str. Dosing and Administration of drugs: oral apply regardless of the meal, the duration of rural use of 5 - 10 days; adults and children over 12 years - the usual dose is 400 mg / day for one or two receiving 200 mg every 12 h daily dose for treatment uncomplicated urinary tract infections is 200 mg. mitis, Str. J01DD08 - Antibacterial agents for systemic use.
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