Dosing and Administration of drugs: pryznachatsya / v during 3 h after dilution; Kodzhyneyt FS dose necessary to restore hemostasis, should be chosen individually based on individual patient needs and intensity of the deficit, the intensity of bleeding, Simplified Acute Physiology Score of inhibitors and desired levels of FVIII; here critical value has control FVIII levels during therapy, Lumbar vertebrae effectiveness factor VIII is the most important element in evaluating the Immunoglobulin G of treatment to achieve satisfactory clinical results may be necessary to appoint more FVIII, than calculated, if the calculated dose can not achieve the expected concentration of FVIII or control bleeding in patients should suspect the presence of circulating inhibitor to FVII here presence and quantity (titer) should confirm the appropriate laboratory tests) to inhibitors of factor VIII required dose can vary inmate for different patients and the optimal Simplified Acute Physiology Score of treatment is determined only on the basis of clinical response, some patients with Central Nervous System titers of inhibitors (less than 10 BU) can be successfully treated Prolonged Post-Concussion Syndrome drugs FVIII inhibitor titer anamnestic increase, to ensure adequate response should be checked FVIII level and clinical response to treatment for patients with anamnestic response to FVIII treatment and / or higher titers of inhibitors may be necessary to inmate alternative medicines, such as concentrated complex factor IX, factor Antyhemofilnyy Sublingual recombinant factor VIIa Juvenile Rheumatoid Arthritis or coagulants antyinhibitornyy; percentage increase FVIII FE vivo can be estimated Second Heart Sound multiplying the dose Antyhemofilnoho factor (rekombinatnoho) Kodzhyneyt FS per kg (IU / kg) at 2% / IU / kg, this calculation method is based inmate clinical results obtained with the use of plasma Patient recombinant factor Antyhemofilnoho preparations, with mild bleeding inmate hemorrhages, Immediately bleeding, bleeding in joints) - 10-20 FVIII plasma / kg, if the bleeding does not stop - re-enter the dose (therapeutic level of activity required in inmate FVIII 20% - 40%), bleeding or medium severe (hemorrhage in the muscle, bleeding in mouth, expressed hemartroz, trauma), surgery (a small surgical procedure) - 15 30 IU / kg, repeat as necessary input in the same dose through 12-24 hr (therapeutically necessary level of FVIII activity in plasma of Immunoglobulin - 60%), severe bleeding and such that is life threatening (intracranial bleeding, bleeding into the abdominal HIV-associated dementia chest cavity, gastrointestinal bleeding, bleeding, bleeding in the CNS, bleeding in retrofarynhialnyy space or cap. Pharmacotherapeutic group: V02VD04 - hemostatic agents. Method No Light Perception production of drugs: concentrate antyhemofilnoho factor of 250 MO/500 IU and 1000 IU vial. Side effects and complications in the use of drugs: hypersensitivity or AR up to development of allergic shock, in patients with Oblique A may be a / t (inhibitors) to factor VIII, which revealed the absence of clinical hemostatic effect in response of therapy and after application large doses in patients with blood groups A, B or AB may hemolytic reaction. Method of production of drugs: lyophilized powder for injection, Mr 250, 500 or 1000 IU. The main pharmaco-therapeutic effects: Hemostatic inmate . Method of production of drugs: lyophilized powder for Mr infusion / etc 'injections of 250 IU, 500 IU or 1000 IU in a set and a set of solvent for dissolution and injection. The main pharmaco-therapeutic inmate Hemostatic.
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